Article
The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response.
Proceedings of the National Academy of Sciences of the United States of America - 27 Mar 2001
Ghbeish N, Tsai C C, Schubiger M, Zhou J Y, Evans R M, McKeown M
Abstract excerpt
The Drosophila homolog of the retinoid X receptor, ultraspiracle (USP), heterodimerizes with the ecdysone receptor (EcR) to form a functional complex that mediates the effects of the steroid molting hormone ecdysone by activating and repressing expression of ecdysone response genes. As with other retinoid X receptor heterodimers, EcR/USP affects gene transcription in a ligand-modulated manner. We used in vivo,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.