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Article

The impact of Fc-γ receptor polymorphisms in elderly patients with diffuse large B-cell lymphoma treated with CHOP with or without rituximab.

Blood - 27 Oct 2011

Ahlgrimm Manfred, Pfreundschuh Michael, Kreuz Markus, Regitz Evi, Preuss Klaus-Dieter, Bittenbring Joerg

Abstract excerpt

Fcγ receptor (FcγR) polymorphisms have been shown to affect rituximab-mediated antibody-dependent cellular cytotoxicity. Of 512 patients with diffuse large B-cell lymphoma treated in the RICOVER-60 trial, carriers of FcγRIII 158 valine homozygous receptors (V/V) presented with a slightly decreased incidence of B-symptoms (158 V/V: 26%, V/F: 35%, phenylalanine receptors [F/F]: 42%; P = .037). Survival curves of...

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Identifiers

PMID: 21900198
DOI: 10.1182/blood-2011-04-346411
PMCID: PMC3208281

Genes

EFS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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