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Article

Effect of FCGR2A and FCGR3A variants on CLL outcome.

Blood - 18 Nov 2010

Dornan David, Spleiss Olivia, Yeh Ru-Fang, Duchateau-Nguyen Guillemette, Dufour Annika, Zhi Jianguo, Robak Tadeusz, Moiseev Sergey I, Dmoszynska Anna, Solal-Celigny Philippe, Warzocha Krzysztof, Loscertales Javier, Catalano John, Afanasiev Boris V, Larratt Loree, Rossiev Viktor A, Bence-Bruckler Isabelle, Geisler Christian H, Montillo Marco, Wenger Michael K, Weisser Martin

Abstract excerpt

Polymorphisms of activating Fc-γ receptors (FCGRs) on natural killer cells and macrophages result in variable affinity for immunoglobulin G1 monoclonal antibodies and subsequently modulate antibody-dependent cellular cytotoxicity (ADCC) activity. Whether single-nucleotide polymorphisms of FCGRs correlate with survival of chronic lymphocytic leukemia (CLL) patients treated with a monoclonal antibody containing...

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Source

Identifiers

PMID: 20705761
DOI: 10.1182/blood-2010-03-272765

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effect of FCGR2A and FCGR3A variants on CLL outcome.PMID 20705761Read ↗

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