Article
FCGR3A gene polymorphisms may correlate with response to frontline R-CHOP therapy for diffuse large B-cell lymphoma.
Blood - 15 Oct 2006
Kim Dong Hwan, Jung Hee Du, Kim Jong Gwang, Lee Je-Jung, Yang Deok-Hwan, Park Yeon Hee, Do Young Rok, Shin Ho Jin, Kim Min Kyoung, Hyun Myung Soo, Sohn Sang Kyun
Abstract excerpt
The precise mechanism of rituximab plus cyclophosphamide/doxorubicin/vincristine/prednisone (R-CHOP) therapy in diffuse large B-cell lymphoma (DLBCL) is not fully elucidated. Besides overcoming bcl-2-mediated chemoresistance, antibody-dependent cellular cytotoxicity (ADCC), which is activated by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
