Article
[Efficacy of rituximab therapy on diffuse large B-cell lymphoma with different Fcgamma RIIIA gene polymorphisms: a prospective study].
Zhonghua yi xue za zhi - 17 Feb 2009
Zhang Wei, Wang Xuan, Duan Ming-Hui, Li Jian, Zhou Dao-Bin
Abstract excerpt
OBJECTIVE: To evaluate the impact of FcgammaRIIIA gene polymorphism on the response to rituximab therapy in newly diagnosed diffuse large B-cell lymphoma (DLBCL). METHODS: Thirty-four patients with newly diagnosed, histologically proven CD20-positive DLBL received rituximab combined chemotherapy (CHOP regimen) for 6 - 8 courses of 21 days. Peripheral blood samples were collected from these 34 patients and 20...
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