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Article

Stage-specific depletion of myosin A supports an essential role in motility of malarial ookinetes

8 Sept 2011

Abstract excerpt

Functional analysis of Plasmodium genes by classical reverse genetics is currently limited to mutants that are viable during erythrocytic schizogony, the pathogenic phase of the malaria parasite where transfection is performed. Here, we describe a conceptually simple experimental approach to study the function of genes essential to the asexual blood stages in a subsequent life cycle stage by a promoter-swap...

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PMID: 21899701
DOI: 10.1111/j.1462-5822.2011.01686.x

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