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Article

Multiple essential functions of Plasmodium falciparum actin-1 during malaria blood-stage development

15 Aug 2017

Abstract excerpt

BACKGROUND: The phylum Apicomplexa includes intracellular parasites causing immense global disease burden, the deadliest of them being the human malaria parasite Plasmodium falciparum, which invades and replicates within erythrocytes. The cytoskeletal protein actin is well conserved within apicomplexans but divergent from mammalian actins, and was primarily reported to function during host cell invasion. However,...

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PMID: 28810863
DOI: 10.1186/s12915-017-0406-2

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