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Artemisinin-Based Antimalarial Drug Therapy: Molecular Pharmacology and Evolving Resistance

4 Jun 2019

Abstract excerpt

The molecular pharmacology of artemisinin (ART)-based antimalarial drugs is incompletely understood. Clinically, these drugs are used in combination with longer lasting partner drugs in several different artemisinin combination therapies (ACTs). ACTs are currently the standard of care against Plasmodium falciparum malaria across much of the world. A harbinger of emerging artemisinin resistance (ARTR), known as...

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PMID: 31167396
DOI: 10.3390/tropicalmed4020089

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