Article
UVC mutagenicity is suppressed in Japanese miso-treated human RSa cells, possibly via GRP78 expression.
Bioscience, biotechnology, and biochemistry - 1 Jan 2011
Jiang Xia, Ren Qian, Chen Shi-Ping, Tong Xiao-Bo, Dong Mei, Sugaya Shigeru, Tanaka Takeshi, Kita Kazuko, Suzuki Nobuo
Abstract excerpt
Little is known about the ability of miso, to modulate mutability in human cells. We have observed increased levels of glucose-regulated protein 78 (GRP78) expression in association with suppression of mutation in human RSa cells irradiated with ultraviolet C (UVC). Here we examined to determine whether miso treatment results in increased GRP78 expression and suppression of UVC mutagenicity in RSa cells....
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