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Article

No major role for 7,8-dihydro-8-oxoguanine in ultraviolet light-induced mutagenesis.

Radiation research - 1 Oct 2005

Kappes Ulrike P, Rünger Thomas M

Abstract excerpt

Oxidative DNA damage, in particular 7,8-dihydro-8-oxoguanine (8-oxoG), has been suggested to mediate mutation formation and malignant transformation after exposure of the skin to long-wave ultraviolet (UVA) light. It is processed primarily by the base excision repair (BER) pathway. The initial step of BER is the removal of the damaged base by a damage-specific DNA-glycosylase, which is 8-oxoG DNA glycosylase...

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Identifiers

PMID: 16187746
DOI: 10.1667/rr3434.1

Genes

OGG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No major role for 7,8-dihydro-8-oxoguanine in ultraviolet light-induced mutagenesis.PMID 16187746Read ↗

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