Article
Down-regulation of molecular chaperone 78-kd glucose-regulated protein/immunoglobulin-binding protein expression involved in enhancement of human RS cell mutability.
Pancreas - 1 Jan 2008
Hirano Junko, Kita Kazuko, Sugaya Shigeru, Ichimura Yoshinobu, Yamamori Hideo, Nakajima Nobuyuki, Suzuki Nobuo
Abstract excerpt
OBJECTIVES: Enhancement of cell mutability via extracellular materials of cancer cells is a crucial event leading to the development of cancers; however, the activation process of mutability is still not well understood. In this study, to identify the regulatory mechanism of cell mutability, we investigated mutability modulated in response to human pancreatic cancer cell-conditioned medium and identified the...
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