Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CETP polymorphisms associate with brain structure, atrophy rate, and Alzheimer's disease risk in an APOE-dependent manner.

Brain imaging and behavior - 1 Mar 2012

Murphy Elizabeth A, Roddey John Cooper, McEvoy Linda K, Holland Dominic, Hagler D J, Dale Anders M, Brewer James B

Abstract excerpt

Two alleles in cholesteryl ester transfer protein (CETP) gene polymorphisms have been disputably linked to enhanced cognition and decreased risk of Alzheimer's disease (AD): the V and A alleles of I405V and C-629A. This study investigates whether these polymorphisms affect brain structure in 188 elderly controls and 318 AD or mild cognitive impairment (MCI) subjects from the Alzheimer's Disease Neuroimaging...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Distribution
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Atrophy

Share to Cholesterol Ester Transfer Proteins

Share to Follow-Up Studies

Share to Magnetic Resonance Imaging

Source

Open in PubMed Open full text

Identifiers

PMID: 21892657
DOI: 10.1007/s11682-011-9137-0
PMCID: PMC4305449

Genes

APOE
CETP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CETP polymorphisms associate with brain structure, atrophy rate, and Alzheimer's disease risk in an APOE-dependent manner.PMID 21892657Read ↗

Association of APOE alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease neuroimaging markers.Semantic proximity Read ↗

Genetic markers of cholesterol transport and gray matter diffusion: a preliminary study of the CETP I405V polymorphism.Semantic proximity Read ↗

A comprehensive analysis of <i>APOE</i> genotype effects on human brain structure in the UK BiobankSemantic proximity Read ↗

Cortical thinning in temporal pole, a core region in Alzheimer’s disease, in non-demented, middle-aged <i>APOE</i> -ε4 and <i>PICALM</i> -AA/AG carriersSemantic proximity Read ↗

Differences in Alzheimer's Disease-Related Pathology Profiles Across Apolipoprotein Groups.Semantic proximity Read ↗

Apolipoprotein E genotype and MRI-detected brain alterations pertaining to neurodegeneration: A systematic reviewSemantic proximity Read ↗

Population-based analysis of cholesteryl ester transfer protein identifies association between I405V and cognitive decline: the Cache County Study.Semantic proximity Read ↗

A comprehensive analysis of APOE genotype effects on human brain structure in the UK Biobank.Semantic proximity Read ↗

Is there association between <i>APOE</i> e4 genotype and structural brain ageing phenotypes, and does that association increase in older age in UK Biobank? (N = 8,395)Semantic proximity Read ↗

Association of a functional polymorphism in the cholesteryl ester transfer protein (CETP) gene with memory decline and incidence of dementia.Semantic proximity Read ↗

Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease.Semantic proximity Read ↗

Impact of APOE-ε alleles on brain structure and cognitive function in healthy older adults: A VBM and DTI replication study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.