Article
Population-based analysis of cholesteryl ester transfer protein identifies association between I405V and cognitive decline: the Cache County Study.
Neurobiology of aging - 1 Jan 2015
Lythgoe Caitlin, Perkes Ammon, Peterson Michael, Schmutz Cameron, Leary Maegan, Ebbert Mark T W, Ridge Perry G, Norton Maria C, Tschanz JoAnn T, Munger Ronald G, Corcoran Christopher D, Kauwe John S K
Abstract excerpt
Cholesterol has been implicated in the pathogenesis of late-onset Alzheimer's disease (LOAD) and the cholesteryl ester transfer protein (CETP) is critical to cholesterol regulation within the cell, making CETP an Alzheimer's disease candidate gene. Several studies have suggested that CETP I405V (rs5882) is associated with cognitive function and LOAD risk, but findings vary and most studies have been conducted...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
