Article
Genetic variation of the alpha subunit of the epithelial Na+ channel influences exhaled Na+ in healthy humans.
Respiratory physiology & neurobiology - 15 Dec 2011
Foxx-Lupo William T, Wheatley Courtney M, Baker Sarah E, Cassuto Nicholas A, Delamere Nicholas A, Snyder Eric M
Abstract excerpt
Epithelial Na(+) channels (ENaC) are located in alveolar cells and are important in β(2)-adrenergic receptor-mediated lung fluid clearance through the removal of Na(+) from the alveolar airspace. Previous work has demonstrated that genetic variation of the alpha subunit of ENaC at amino acid 663...
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