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Article

'Difficult to diagnose' desmoid tumours: a potential role for CTNNB1 mutational analysis.

Histopathology - 1 Aug 2011

Colombo Chiara, Bolshakov Svetlana, Hajibashi Shohrae, Lopez-Terrada Lola, Wang Wei-Lien, Rao Priya, Benjamin Robert S, Lazar Alexander J, Lev Dina

Abstract excerpt

AIMS: The utility of CTNNB1 (encoding β-catenin) genotyping for diagnosing sporadic desmoid tumours (DT) when traditional clinicopathological parameters were inconclusive was evaluated. METHODS AND RESULTS: Cases included were: (i) new primary lesions where initial DT diagnosis was inconclusive; and (ii) possible recurrent DT versus scar. Formalin-fixed paraffin-embedded (FFPE) tissues were obtained via needle...

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Identifiers

PMID: 21884214
DOI: 10.1111/j.1365-2559.2011.03932.x

Genes

CTNNB1

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