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Article

An 8-fold beta alpha barrel protein with redundant folding possibilities.

Protein engineering - 1 Mar 1990

Luger K, Szadkowski H, Kirschner K

Abstract excerpt

Protein sequences containing redundant segments of secondary structure at both termini have the choice a priori of folding into several possible circularly permuted variants of the wild-type tertiary structure. To test this hypothesis the gene of phosphoribosyl anthranilate isomerase from yeast, which is a single-domain 8-fold beta alpha barrel protein, was modified to produce a 10-fold beta alpha homologue in...

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PMID: 2188262
DOI: 10.1093/protein/3.4.249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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