Article
An 8-fold beta alpha barrel protein with redundant folding possibilities.
Protein engineering - 1 Mar 1990
Luger K, Szadkowski H, Kirschner K
Abstract excerpt
Protein sequences containing redundant segments of secondary structure at both termini have the choice a priori of folding into several possible circularly permuted variants of the wild-type tertiary structure. To test this hypothesis the gene of phosphoribosyl anthranilate isomerase from yeast,...
Topics
- Aldose-Ketose Isomerases
- Amino Acid Sequence
- Base Sequence
- Carbohydrate Epimerases
- Escherichia coli
- Genetic Variation
- Molecular Sequence Data
- Plasmids
- Protein Conformation
- Transfection
- Yeasts