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Article

Refolding the unfoldable: A systematic approach for renaturation of Bacillus circulans xylanase.

Protein science : a publication of the Protein Society - 1 Aug 2017

Kötzler Miriam P, McIntosh Lawrence P, Withers Stephen G

Abstract excerpt

Xylanases are important polysaccharide-cleaving catalysts for the pulp and paper, animal feeds and biofuels industries. They have also proved to be valuable model systems for understanding enzymatic catalysis, with one of the best studied being the GH11 xylanase from Bacillus circulans (Bcx). However, proteins from this class are very recalcitrant to refolding in vitro. This both limits their high level...

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Identifiers

PMID: 28466501
DOI: 10.1002/pro.3181
PMCID: PMC5521550

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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