Article
Gene set analysis and network analysis for genome-wide association studies.
Cold Spring Harbor protocols - 1 Sept 2011
Pedroso Inti, Breen Gerome
Abstract excerpt
The application of high-throughput genotyping in humans has yielded numerous insights into the genetic basis of human phenotypes and an unprecedented amount of genetic data. Genome-wide association studies (GWAS) have increased in number in recent years, but the variants that have been found have generally explained only a tiny proportion of the estimated genetic contribution to phenotypic variation. This article...
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