Article
Genetic effects of 2-aminopurine in mammalian cells.
Mutagenesis - 1 Mar 1990
Speit G, Garkov S, Haupter S, Köberle B
Abstract excerpt
The effects of 2-aminopurine (APur) on mutations, sister-chromatid exchanges (SCEs) and proliferation were investigated in V79 cells by means of cytogenetic and flowcytometric experiments. APur did not induce SCEs after a 3-h treatment before the addition of BrdUrd but SCE frequencies were increased after treatment for two cell cycles in the presence of BrdUrd. SCEs were mainly produced during the second cell...
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