Genetic effects of 2-aminopurine in mammalian cells.

doi:10.1093/mutage/5.2.185

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Article

Genetic effects of 2-aminopurine in mammalian cells.

Mutagenesis - 1 Mar 1990

Speit G, Garkov S, Haupter S, Köberle B

Abstract excerpt

The effects of 2-aminopurine (APur) on mutations, sister-chromatid exchanges (SCEs) and proliferation were investigated in V79 cells by means of cytogenetic and flowcytometric experiments. APur did not induce SCEs after a 3-h treatment before the addition of BrdUrd but SCE frequencies were increa...

Topics

2-Aminopurine
Adenine
Aneuploidy
Animals
Cells, Cultured
Cricetinae
DNA
DNA Replication
Flow Cytometry
Fluorescence
Mutation
Sister Chromatid Exchange

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