Article
Association of cognitive performance with interleukin-6 receptor Asp358Ala polymorphism in healthy adults.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2012
Sasayama Daimei, Hori Hiroaki, Teraishi Toshiya, Hattori Kotaro, Ota Miho, Matsuo Junko, Kawamoto Yumiko, Kinoshita Yukiko, Amano Naoji, Kunugi Hiroshi
Abstract excerpt
Wechsler adult intelligence scale-revised was performed in 576 healthy adults to examine whether a functional polymorphism (Asp358Ala) of the IL-6 receptor (IL-6R) gene is associated with cognitive performance. Verbal intelligence quotient in Asp homozygotes was significantly higher compared to Ala carriers (P = 0.005). Compared to Ala carriers, Asp homozygotes performed better in the verbal subtests requiring...
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