Article
P-selectin 1087G/A polymorphism is associated with neuropsychological test performance in older adults with cardiovascular disease.
Stroke - 1 Sept 2009
Gunstad John, Benitez Andreana, Hoth Karin F, Spitznagel Mary Beth, McCaffery Jeanne, McGeary John, Kakos Lynn S, Poppas Athena, Paul Robert H, Jefferson Angela L, Sweet Lawrence H, Cohen Ronald A
Abstract excerpt
BACKGROUND AND PURPOSE: There is growing evidence that the cell adhesion molecule P-selectin (SELP) contributes to the adverse vascular processes that promote cognitive impairment in individuals with cardiovascular disease. Previous research has shown that SELP genotypes moderate circulating levels of P-selectin and that patients undergoing coronary artery bypass graft with the SELP 1087A allele were less likely...
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