Article
Association of interleukin-1β genetic polymorphisms with cognitive performance in elderly females without dementia.
Journal of human genetics - 1 Aug 2011
Sasayama Daimei, Hori Hiroaki, Teraishi Toshiya, Hattori Kotaro, Ota Miho, Matsuo Junko, Kawamoto Yumiko, Kinoshita Yukiko, Higuchi Teruhiko, Amano Naoji, Kunugi Hiroshi
Abstract excerpt
Interleukin-1β (IL-1β) is considered to have a role in age-related cognitive decline. A recent study has shown that a promoter polymorphism of the IL-1β gene (rs16944) is associated with cognitive performance in elderly males without dementia. In this study, we examined whether polymorphisms of the IL-1β gene also influence cognitive functions in elderly females. Cognitive functions were assessed by the Wechsler...
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