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Article

Association of forkhead box P3 gene polymorphisms with premature ovarian insufficiency in Chinese women.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Mar 2021

Zhong Chenyi, Wang Wanyue, Pu Danhua, Wang Huiyuan, Tan Rongrong, Wu Jie

Abstract excerpt

OBJECTIVE: Forkhead box P3 (FOXP3), a transcription factor, is regarding critical regulator of the function of regulatory T (Treg) cells and plays a crucial role in the development of autoimmune diseases. Premature ovarian insufficiency (POI) is an autoimmune disease; however, little is known about the association between FOXP3 variants and the susceptibility to POI. METHODS: Long-range polymerase chain reaction...

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PMID: 33274669
DOI: 10.1080/09513590.2020.1854716

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