Article
FoxP3 gene promoter polymorphism affects susceptibility to preeclampsia.
Human immunology - 1 Dec 2016
Norouzian Marzieh, Rahimzadeh Mahsa, Rajaee Minoo, Arabpour Fahimeh, Naderi Nadereh
Abstract excerpt
BACKGROUND: Preeclampsia (PE) is a multifactorial pregnancy disorder and is a major cause of maternal morbidity and mortality. Despite intense study, the pathophysiology of preeclampsia remains enigmatic. Recent studies have reported that regulatory T cells (Tregs) is linked with PE. It is well identified that FoxP3/Scurfin is involved in development and function of Tregs. However, the association between PE and...
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