Article
Association study of FOXP3 gene and the risk of 0020 pre-eclampsia.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2018
Gholami Milad, Mirfakhraie Reza, Pirjani Reihaneh, Taheripanah Robabeh, Bayat Sahar, Daryabari Seyyedeh Anita, Noori Matina, Ghaderian Sayyed Mohamad Hossein
Abstract excerpt
Pre-eclampsia (PE) is a multifactorial pregnancy disorder, with serious consequences for both the mother and the fetus. Despite intense studies, the pathophysiology of PE remains enigmatic. Previous studies suggested that Treg dysfunction is involved in the pathogenesis of PE. We hypothesized that functional variants of the FOXP3 gene might be associated with PE via dysregulation of Treg cells. Of the 276...
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