Article
The role of two common FOXP3 gene promoter polymorphisms in preeclampsia in a Turkish population: a case-control study.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology - 1 May 2020
Cekin Nilgun, Pinarbasi Ergun, Esra Bildirici Aslihan, Okten Hatice, Yanik Ali, Sonmez Gamze
Abstract excerpt
Preeclampsia (PE), which occurs in approximately 5% of pregnancies worldwide and constitutes clinically serious complications in 2-3%, is one of the leading causes of maternal and prenatal morbidity and mortality. Recent studies report that regulatory T (Treg) cells, which act as immunosuppressant, are associated with PE. It is clearly defined that FOXP3/Scurfin (Forkhead Box P3) is involved in the development...
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