Article
Immunocytochemically detectable TGF-beta associated with malignancy in thyroid epithelial neoplasia.
Growth factors (Chur, Switzerland) - 1 Jan 1990
Jasani B, Wyllie F S, Wright P A, Lemoine N R, Williams E D, Wynford-Thomas D
Abstract excerpt
The possible role of changes in TGF-beta expression in the multistage development of thyroid cancer was assessed. The presence of TGF-beta 1 in thyroid epithelial cells was analyzed in sections of normal and tumor tissue using an immunoperoxidase technique employing an antibody directed against t...
Topics
- Adenocarcinoma
- Adenoma
- Carcinoma, Papillary
- Genes, ras
- Humans
- Immunohistochemistry
- Mutation
- Thyroid Gland
- Thyroid Neoplasms
- Transforming Growth Factors