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Article

The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting.

Proceedings of the National Academy of Sciences of the United States of America - 1 May 1990

Flower A M, McHenry C S

Abstract excerpt

The tau and gamma subunits of DNA polymerase III holoenzyme are both products of the dnaX gene. Since tau and gamma are required as stoichiometric components of the replicative complex, a mechanism must exist for the cell to coordinate their synthesis and ensure that both subunits are present in an adequate quantity and ratio for assembly. We have proposed that gamma is produced by a translational frameshift...

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PMID: 2187190
DOI: 10.1073/pnas.87.10.3713
PMCID: PMC53973

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