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Article

Identification of the tRNA anticodon recognition site of Escherichia coli methionyl-tRNA synthetase.

Biochemistry - 6 Mar 1990

Ghosh G, Pelka H, Schulman L H

Abstract excerpt

We have previously shown that the anticodon of methionine tRNAs contains most, if not all, of the nucleotides required for specific recognition of tRNA substrates by Escherichia coli methionyl-tRNA synthetase [Schulman, L. H., & Pelka, H. (1988) Science 242, 765-768]. Previous cross-linking experiments have also identified a site in the synthetase that lies within 14 A of the anticodon binding domain [Leon, O., &...

Topics

Amino Acyl-tRNA Synthetases
Anticodon
Base Sequence
Escherichia coli
Kinetics
Methionine-tRNA Ligase
Mutation
RNA, Transfer
RNA, Transfer, Amino Acyl
Transcription, Genetic

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Identifiers

PMID: 2186810
DOI: 10.1021/bi00461a003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2186810-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Identification of the tRNA anticodon recognition site of Escherichia coli methionyl-tRNA synthetase.PMID 2186810Read ↗

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