Article
Protein folding: Vexing debates on a fundamental problem.
Biophysical chemistry - 1 May 2016
Gianni Stefano, Jemth Per
Abstract excerpt
The folding of proteins has been at the heart of protein chemistry and biophysics ever since the pioneering experiments by the labs of Fred Richards and Christian Anfinsen. But, despite nearly 60 years of intense research, there are unresolved issues and a lively debate regarding some aspects of this fundamental problem. In this review we give a personal account on some key topics in the field: (i) the nature of...
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