Article
Analysis of polymorphism in the survivin gene promoter as a potential risk factor for head and neck cancers development.
Srpski arhiv za celokupno lekarstvo - 1 Jan 2000
Kostić Marija, Nikolić Nadja, Ilić Branislav, Carkić Jelena, Milenković Sanja, Vukadinović Miroslav
Abstract excerpt
INTRODUCTION: Association studies have shown that gene polymorphisms in various classes of genes can modulate cancer risk. The -31G/C polymorphism in the promoter of survivin gene, affects the expression of the anti-apoptotic protein survivin which in turn may predispose an individual to some types of cancer. OBJECTIVE: The aim of the study was to determine whether the survivin promoter -31G/C polymorphism could...
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