Article
Polymorphisms in the survivin gene and the risk of lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Apr 2008
Jang Jin Sung, Kim Kyung Mee, Kang Kyung Hee, Choi Jin Eun, Lee Won Kee, Kim Chang Ho, Kang Young Mo, Kam Sin, Kim In-San, Jun Jae Eun, Jung Tae Hoon, Park Jae Yong
Abstract excerpt
BACKGROUND: Survivin is an apoptosis inhibitor and plays an important role in the development and progression of cancer. Polymorphisms in the survivin gene may influence survivin production or activity, thereby modulating susceptibility to lung cancer. To test this hypothesis, we investigated the association between survivin polymorphisms and the risk of lung cancer in a Korean population. METHODS: We first...
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