Article
Chemical-Genetic Approaches for Exploring Mode of Action of Antifungal Compounds in the Fungal Pathogen Candida albicans.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2023
Robbins Nicole, Ketela Troy, Kim Sang Hu, Cowen Leah E
Abstract excerpt
Candida albicans is a prevalent fungal pathogen of humans that can cause both superficial and life-threatening disease, primarily in immunocompromised populations. Currently, antifungal drug classes available to treat fungal infections remain limited and the emergence of drug-resistant strains threatens antifungal efficacy, necessitating the discovery and development of additional therapeutics. The construction...
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