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Article

miRNA-mediated feedback inhibition of JAK/STAT morphogen signalling establishes a cell fate threshold.

Nature cell biology - 21 Aug 2011

Yoon Wan Hee, Meinhardt Hans, Montell Denise J

Abstract excerpt

Patterns of cell fates generated by morphogens are critically important for normal development; however, the mechanisms by which graded morphogen signals are converted into all-or-none cell fate responses are incompletely understood. In the Drosophila ovary, high and sustained levels of the secreted morphogen Unpaired (Upd) specify the migratory border-cell population by activating the signal transducer and...

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Identifiers

PMID: 21857668
DOI: 10.1038/ncb2316
PMCID: PMC3167036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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miRNA-mediated feedback inhibition of JAK/STAT morphogen signalling establishes a cell fate threshold.PMID 21857668Read ↗

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