Article
Drosophila RalA is essential for the maintenance of Jak/Stat signalling in ovarian follicles.
EMBO reports - 1 Jul 2008
Ghiglione Christian, Devergne Olivier, Cerezo Delphine, Noselli Stéphane
Abstract excerpt
Small GTPases of the Ras-like (Ral) family are crucial for signalling functions in both normal and cancer cells; however, their role in a developing organism is poorly understood. Here, we identify the Drosophila Ral homologue RalA as a new key regulator of polar-cell differentiation during oogenesis. Polar cells have a crucial role in patterning the egg chamber and in recruiting border cells, which undergo...
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