Article
Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2005
Gelernter Joel, Panhuysen Carolien, Weiss Roger, Brady Kathleen, Hesselbrock Victor, Rounsaville Bruce, Poling James, Wilcox Marsha, Farrer Lindsay, Kranzler Henry R
Abstract excerpt
Risk for cocaine dependence (CD) is genetically influenced. We recruited a sample of small nuclear families (528 full and 155 half sibpairs) with at least one subject affected with CD. The sample was classified via Bayesian clustering as 45.5% European American (EA) and 54.5% African American (AA). Assessment, via the Semi-Structured Assessment for Drug Dependence and Alcoholism, allowed for detailed evaluation...
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