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Article

Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2012

Yang Bao-Zhu, Han Shizhong, Kranzler Henry R, Farrer Lindsay A, Elston Robert C, Gelernter Joel

Abstract excerpt

Multiple substance dependence (MSD) trait comorbidity is common, and MSD patients are often severely affected clinically. While shared genetic risks have been documented, so far there has been no published report using the linkage scan approach to survey risk loci for MSD as a phenotype. A total of 1,758 individuals in 739 families [384 African American (AA) and 355 European American (EA) families] ascertained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22354695
DOI: 10.1002/ajmg.b.32037
PMCID: PMC3920832

Genes

CLOCK
GABRA4
GABRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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