Article
Genome-wide co-expression analysis in multiple tissues.
PloS one - 1 Jan 2008
Grieve Ian C, Dickens Nicholas J, Pravenec Michal, Kren Vladimir, Hubner Norbert, Cook Stuart A, Aitman Timothy J, Petretto Enrico, Mangion Jonathan
Abstract excerpt
Expression quantitative trait loci (eQTLs) represent genetic control points of gene expression, and can be categorized as cis- and trans-acting, reflecting local and distant regulation of gene expression respectively. Although there is evidence of co-regulation within clusters of trans-eQTLs, the extent of co-expression patterns and their relationship with the genotypes at eQTLs are not fully understood. We have...
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