Article
Mutagenicity of isoquinoline alkaloids, especially of the aporphine type.
Mutation research - 1 Apr 1990
Nozaka T, Watanabe F, Tadaki S, Ishino M, Morimoto I, Kunitomo J, Ishii H, Natori S
Abstract excerpt
The mutagenicity of 44 isoquinoline alkaloids was tested in Salmonella typhimurium TA100 and TA98 in the presence or absence of S9 mix. The alkaloids tested included compounds from the isoquinoline, benzylisoquinoline, bisbenzylisoquinoline, monoterpene isoquinoline, berberine, morphinane, hasubanan, benzo[c]phenanthridine and aporphine groups. Among the alkaloids tested, liriodenine was the most potent mutagen...
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