Article
Genotoxicity of pyrrolizidine alkaloids.
Journal of applied toxicology : JAT - 1 Apr 2010
Chen Tao, Mei Nan, Fu Peter P
Abstract excerpt
Pyrrolizidine alkaloids (PAs) are common constituents of many plant species around the world. PA-containing plants are probably the most common poisonous plants affecting livestock and wildlife. They can inflict harm to humans through contaminated food sources, herbal medicines and dietary supplements. Half of the identified PAs are genotoxic and many of them are tumorigenic. The mutagenicity of PAs has been...
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