Article
Cloning and characterization of functional subtype A HIV-1 envelope variants transmitted through breastfeeding.
Current HIV research - 1 Mar 2007
Rainwater Stephanie M J, Wu Xueling, Nduati Ruth, Nedellec Rebecca, Mosier Donald, John-Stewart Grace, Mbori-Ngacha Dorothy, Overbaugh Julie
Abstract excerpt
Previous studies of HIV-1 variants transmitted from mother-to-infant have focused primarily on computational analyses of partial envelope gene sequences, rather than analyses of functional envelope variants. There are very few examples of well-characterized functional envelope clones from mother-infant pairs, especially from envelope variants representing the most prevalent subtypes worldwide. To address this, we...
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