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Article

Apoptotic cell-based therapies against transplant rejection: role of recipient’s dendritic cells

5 Feb 2010

Abstract excerpt

One of the ultimate goals in transplantation is to develop novel therapeutic methods for induction of donor-specific tolerance to reduce the side effects caused by the generalized immunosuppression associated to the currently used pharmacologic regimens. Interaction or phagocytosis of cells in early apoptosis exerts potent anti-inflammatory and immunosuppressive effects on antigen (Ag)-presenting cells (APC) like...

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PMID: 20140521
DOI: 10.1007/s10495-010-0469-9

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