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Article

Evidence for a complex of transcription factor IIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping.

The Journal of biological chemistry - 30 Sept 2011

Medler Scott, Al Husini Nadra, Raghunayakula Sarita, Mukundan Banupriya, Aldea Ashley, Ansari Athar

Abstract excerpt

Gene looping, defined as the interaction of the promoter and the terminator regions of a gene during transcription, requires transcription factor IIB (TFIIB). We have earlier demonstrated association of TFIIB with the distal ends of a gene in an activator-dependent manner (El Kaderi, B., Medler, S., Raghunayakula, S., and Ansari, A. (2009) J. Biol. Chem. 284, 25015-25025). The presence of TFIIB at the 3' end of a...

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Identifiers

PMID: 21835917
DOI: 10.1074/jbc.M110.193870
PMCID: PMC3190792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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