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Article

Role for gene looping in intron-mediated enhancement of transcription.

Proceedings of the National Academy of Sciences of the United States of America - 29 May 2012

Moabbi Aboudi M, Agarwal Neha, El Kaderi Belal, Ansari Athar

Abstract excerpt

Intron-containing genes are often transcribed more efficiently than nonintronic genes. The effect of introns on transcription of genes is an evolutionarily conserved feature, being exhibited by such diverse organisms as yeast, plants, flies, and mammals. The mechanism of intron-mediated transcriptional activation, however, is not entirely clear. To address this issue, we inserted an intron in INO1, which is a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22586116
DOI: 10.1073/pnas.1112400109
PMCID: PMC3365183

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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