Article
Absence of gene mutations in KIT-positive carcinoma showing thymus-like elements of the thyroid.
Human pathology - 1 Mar 2012
Pan Yi, Zhao Xiulan, Yang Jilong, Deng Jingyu, Zhan Zhongli, Luo Ye, Li Qi, Guo Yan, Zhai Qiongli, Sun Baocun
Abstract excerpt
KIT, a tyrosine kinase receptor protein encoded by the proto-oncogene c-kit, is overexpressed in human neoplasms such as gastrointestinal stromal tumors and thymic squamous cell carcinoma. However, the role of KIT expression and mutations in carcinoma showing thymus-like elements is not fully understood. In the current study, 8 cases of carcinoma showing thymus-like elements were reported, and immunohistochemical...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
