Article
[Therapy-relevant mutations of receptor tyrosine kinases in malignant thymomas and thymic carcinomas: a therapeutic perspective].
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 2007
Ströbel P, Knop S, Einsele H, Müller-Hermelink H K, Marx A
Abstract excerpt
UNLABELLED: 50-70% of patients with malignant thymic epithelial tumors (thymomas or thymic carcinomas) cannot be cured by current treatment strategies and are therefore candidates for second line therapies. METHODS: Malignant thymomas and thymic squamous cell carcinomas (TSCC) were analyzed by genomic sequencing and functional tests using ex vivo explant cell cultures to study alterations of the receptor tyrosine...
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