Article
Comprehensive genomic analysis reveals clinically relevant molecular distinctions between thymic carcinomas and thymomas.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2009
Girard Nicolas, Shen Ronglai, Guo Tianhua, Zakowski Maureen F, Heguy Adriana, Riely Gregory J, Huang James, Lau Christopher, Lash Alex E, Ladanyi Marc, Viale Agnes, Antonescu Cristina R, Travis William D, Rusch Valerie W, Kris Mark G, Pao William
Abstract excerpt
PURPOSE: Thymomas and thymic carcinomas are rare intrathoracic malignancies that can be invasive and refractory to conventional treatment. Because these tumors both originate from the thymus, they are often grouped together clinically. However, whether the underlying biology of these tumors warrants such clustering is unclear, and the optimum treatment of either entity is unknown. EXPERIMENTAL DESIGN: All thymic...
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