Article
Aberrant methylation: common in thymic carcinomas, rare in thymomas.
Oncology reports - 1 Dec 2005
Suzuki Makoto, Chen Hong, Shigematsu Hisayuki, Ando Soichiro, Iida Tomohiko, Nakajima Takahiro, Fujisawa Takehiko, Kimura Hideki
Abstract excerpt
Thymic carcinoma, which is a rare epithelial neoplasm of the thymus gland, is different from thymoma in its clinical and pathological features. To clarify the mechanism underlying the aggressive behavior of thymic carcinoma, we examined the clinicopathologic features, aberrant methylation patterns of the tumor suppressor genes, and epidermal growth factor receptor (EGFRs) mutation in both thymic carcinomas and...
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