Article
C-KIT mutation in thymic carcinomas.
Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Jan 2020
Terzi Neslihan, Yilmaz Ismail, Batur Sebnem, Yegen Gulcin, Yol Cansu, Arikan Evsen, Oz Aysim
Abstract excerpt
Thymic epithelial tumours are rare malignancies of the anterior superior mediastinum. Several studies have analysed the presence of c-KIT mutations in thymic carcinoma. Immunohistochemical c-KIT expression and mutations in exons 8, 9, 11, 13, 14, 17, and 18 of the KIT gene and in the promoter region of the TERT gene (chr5, 1,295,228C>T/A and 1,295,250C>T) were analysed by PCR based direct sequencing using...
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