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Article

CpG islands undermethylation in human genomic regions under selective pressure.

PloS one - 1 Jan 2011

Cocozza Sergio, Akhtar Most Mauluda, Miele Gennaro, Monticelli Antonella

Abstract excerpt

DNA methylation at CpG islands (CGIs) is one of the most intensively studied epigenetic mechanisms. It is fundamental for cellular differentiation and control of transcriptional potential. DNA methylation is involved also in several processes that are central to evolutionary biology, including phenotypic plasticity and evolvability. In this study, we explored the relationship between CpG islands methylation and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21829712
DOI: 10.1371/journal.pone.0023156
PMCID: PMC3149076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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